Ace Your Nutrition Challenge 2026 – Fuel Your Mind and Body!

Fat-soluble vitamins A, D, E, and K are stored in the liver and adipose tissue and are absorbed with dietary fats. Because they can accumulate, taking high doses carries a risk of toxicity. When liver disease is present, the liver’s ability to metabolize, store, and release these vitamins is altered, making it easier to end up with abnormal levels even with standard supplementation. That’s why dosing fat-soluble vitamins must be approached with extra caution in liver disease. In contrast, vitamin C is water-soluble and excess is usually excreted, iron is a mineral, and kidney failure affects other processes more than the storage of fat-soluble vitamins, so they don’t require the same dosing caution for these vitamins.